Protein name:
Metalloproteinase inhibitor 3 ;
Alternative:
Tissue inhibitor of metalloproteinases 3 (TIMP-3) ;Protein MIG-5 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with EFEMP1.
Function:
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
Subcellular Location:
Secreted
extracellular space
extracellular matrix
Protein Attributes:
50:
MTPWLGLIVL | LGSWSLGDWG | AEACTCSPSH | PQDAFCNSDI | VIRAKVVGKK |
100:
LVKEGPFGTL | VYTIKQMKMY | RGFTKMPHVQ | YIHTEASESL | CGLKLEVNKY |
150:
QYLLTGRVYD | GKMYTGLCNF | VERWDQLTLS | QRKGLNYRYH | LGCNCKIKSC |
200:
YYLPCFVTSK | NECLWTDMLS | NFGYPGYQSK | HYACIRQKGG | YCSWYRGWAP |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Bovine
Human
Chicken
Rabbit
Rat
ELISA Kit for Human Metalloproteinase inhibitor 3
ELISA Kit for Human Metalloproteinase inhibitor 3
ELISA Kit for Human Metalloproteinase inhibitor 3
ELISA Kit for Human Metalloproteinase inhibitor 3
ELISA Kit for Human Metalloproteinase inhibitor 3
ELISA Kit for Human Metalloproteinase inhibitor 3
CLIA Kit for Human Metalloproteinase inhibitor 3
CLIA Kit for Human Metalloproteinase inhibitor 3
CLIA Kit for Human Metalloproteinase inhibitor 3
CLIA Kit for Human Metalloproteinase inhibitor 3
CLIA Kit for Human Metalloproteinase inhibitor 3
CLIA Kit for Human Metalloproteinase inhibitor 3
Polyclonal Antibody for Human Metalloproteinase inhibitor 3
Polyclonal Antibody for Human Metalloproteinase inhibitor 3
Polyclonal Antibody for Human Metalloproteinase inhibitor 3
Polyclonal Antibody for Human Metalloproteinase inhibitor 3
Polyclonal Antibody for Human Metalloproteinase inhibitor 3
Polyclonal Antibody for Human Metalloproteinase inhibitor 3
Monoclonal Antibody for Human Metalloproteinase inhibitor 3
Monoclonal Antibody for Human Metalloproteinase inhibitor 3
Monoclonal Antibody for Human Metalloproteinase inhibitor 3
Monoclonal Antibody for Human Metalloproteinase inhibitor 3
Monoclonal Antibody for Human Metalloproteinase inhibitor 3
Monoclonal Antibody for Human Metalloproteinase inhibitor 3
Protein for Human Metalloproteinase inhibitor 3
Protein for Human Metalloproteinase inhibitor 3
Protein for Human Metalloproteinase inhibitor 3
Protein for Human Metalloproteinase inhibitor 3
Protein for Human Metalloproteinase inhibitor 3
Protein for Human Metalloproteinase inhibitor 3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[
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[
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[
Abstract ]
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
12.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Pancreas .
13.
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Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 14-211
tissue :
Placenta .
14.
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Cited for : PROTEIN SEQUENCE OF 24-41
15.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 42-211
tissue :
Placenta .
16.
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Cited for : INTERACTION WITH EFEMP1
17.
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Cited for : X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 24-144 IN COMPLEX WITH TACE;DISULFIDE BONDS
18.
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Cited for : VARIANTS SFD CYS-191 AND CYS-204
19.
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Cited for : VARIANT SFD CYS-179
20.
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Cited for : VARIANT SFD CYS-190
21.
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Cited for : VARIANT SFD CYS-191
22.
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Cited for : VARIANT SFD CYS-189